Wound Care Certification Practice Exam 2025 – Complete Prep Guide

Uncontrolled blood glucose levels significantly impair wound healing due to their detrimental effects on various cellular functions that are critical for the healing process. High blood glucose concentrations can lead to glycosylation of proteins, which alters their functional integrity and reduces their effectiveness. Specifically, elevated glucose levels reduce collagen synthesis, a fundamental component of the wound healing cascade. Collagen is essential for providing structural support in the healing tissue, and any reduction in its synthesis can lead to delayed healing, increased risk of infection, and ultimately, poorer outcomes in wound repair.

Additionally, uncontrolled blood glucose can impair angiogenesis (the formation of new blood vessels), inflammatory response, and the function of immune cells, further exacerbating the wound healing process. It’s crucial for individuals with wounds, especially those with diabetes, to maintain controlled blood glucose levels to promote optimal healing.